Tirz is a synthetic 39-amino-acid dual agonist peptide for GLP-1 and GIP receptors, revolutionizing obesity and T2D research with superior weight loss (up to 22.5%) and glycemic control.

Peptide Sequence

YXEGTFTSDYSIXLDKIAQKAFVQWLIAGGPSSGAPPPS, where X2/X13=Aib (α-aminoisobutyric acid), K20 acylated with C20 fatty diacid via γ-Glu linker for weekly dosing.

Research Benefits

Reduces HbA1c (-2.11% at 5mg), body weight (-15.2kg at 15mg), promotes lipolysis, insulin release, and BMI improvements vs. comparators. Lowers MACE/MAKE risks, inflammation, and supports CV/kidney outcomes.

Product Specifications

• Purity: 99%+ HPLC-tested lyophilized.

• MW: ~4813 Da.

• Dosing Insight: Weekly SC for metabolic models.

• Storage: -20°C lyophilized.